Download PDF by Roger L. Lundblad: Biotechnology of Plasma Proteins (Protein Science)

By Roger L. Lundblad

The fractionation of human blood plasma will be thought of to be a mature undefined, with the elemental expertise, alcohol fractionation, relationship again at the least to the Forties. the various items defined within the present paintings were licensed biologics because the Fifties. the knowledge amassed from the advance of plasma proteins has proved important to the improvement of recombinant healing proteins.

Discussing the position of plasma proteins in present biotechnology, Biotechnology of Plasma Proteins describes the protein composition of human plasma, the fractionation of plasma to acquire healing proteins, and the research of those items. It delineates the trail from plasma items to recombinant items, and highlights items from albumin, intravenous immunoglobins, and coagulation. It deals a complete assessment of present thoughts for the research of proteins together with electrophoresis, chromatography, spectrophotometry, mass spectrometry, and updates now not released due to the fact 1975.

Key Topics

Protein Composition of Plasma

  • Proteomic equipment for plasma protein analysis

  • Plasma protein biomarkers

  • Validation of biomarkers

  • Assays for plasma biomarkers

Methods for the research of Protein Products

  • Assay improvement and validation

  • Electrophoresis

  • Chromatography

  • Immunoassay

  • Mass spectrometry

  • Raman spectroscopy

Plasma Fractionation: ancient and smooth Methods

  • Development of Cohn alcohol fractionation

  • Industrial methods

  • Development of chromatographic methods

Plasma Protein items of healing Value

  • Albumin

  • Intravenous immunoglobulin

  • Coagulation products

  • Growth factors

  • Wound management

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